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The Insides Company

The Insides Company

The Insides Company is a pioneer in chyme reinfusion therapy, focused on developing specialised medical devices that support patients with intestinal failure and conditions involving intestinal discontinuity. These include high-output stomas, enterocutaneous fistulas, and postoperative situations where the normal digestive pathway is interrupted.

Their flagship technology, The Insides System, is the first purpose-designed platform that enables the safe and controlled reinfusion of intestinal chyme back into the distal gut. By returning the patient's own digestive fluids—rather than discarding them, the system helps restore physiological digestion, improve hydration and nutrient absorption, and support the recovery of overall intestinal function.

The Insides Company's mission, "refeed and restore", reflects their commitment to advancing gut-preserving therapies and improving outcomes for patients who face prolonged nutritional losses or risk of intestinal failure. Through ongoing clinical collaboration and innovation, the company continues to expand global access to chyme reinfusion therapy and introduce a new standard of care for complex enteric conditions.

Chyme Reinfusion Therapy

The Insides® System& The Insides® Channel

Purpose-built chyme reinfusion therapy for intestinal failure and rehabilitation. The Insides System enables safe, automated reinfusion to help patients resume oral feeding and reduce or wean off parenteral nutrition. The Insides Channel facilitates the transfer of chyme from one ostomy appliance to another.

Automated CRT Patient-managed Reduced PN dependence Clinician-validated

The Insides System

Automated chyme reinfusion via magnetically coupled driver and pump, designed to simplify handling and support intestinal rehabilitation.

  • The Insides Driver connects magnetically to The Insides Pump via the outside of the patient’s ostomy appliance.
  • The Insides Pump sits within the ostomy appliance, and pumps the chyme into the distal intestine via The Insides Tube.
  • The Insides Tube inserts into the distal intestine and connected to The Insides Pump, serving as a conduit for chyme.

The Insides Channel

Purpose-built catheter solution to establish distal access and enable CRT using The Insides System.

  • The Insides Channel Tubing allows the flow of chyme between two ostomy appliances.
  • The Insides Pump Sits within the proximal ostomy appliance, allowing the transfer of chyme across The Insides Channel Tubing, into the Distal ostomy appliance.
  • The Insides Channel Connector Enables the connection between ostomy appliances, allowing two ostomy appliances to be linked together.
The Insides System
The Insides Channel

Clinical & Economical Benefits

BenefitDescription
Earlier return to oral feedingPatients able to recommence oral feeding.
Improved nutritional outcomeIncrease in nutritional risk index by 10.9 (± 9.5) with a 85% reduction in intestinal losses.
Improved restoration of gut functionLimiting gut atrophy and inflammation.
Improved renal functionPrevents dehydration and reduces the potential for chronic kidney disease.
Improved liver function53% reduction in plasma liver test abnormalities.
Wean off Parenteral Nutrition>91% of patients weaned off parenteral nutrition within a median of 2 days (± 9).

To learn more about The Insides Company, please visit www.theinsides.co, or contact us for more information.